Effervescent vitamin C tablets and its quality control

Erosive potential of vitamin and vitamin+mineral effervescent tablets.

The extrinsic sources for erosion-causing acids are primarily acidic beverages and foodstuffs. Effervescent tablets also contain organic acids (e.g. citric, tartaric, malic) in order to form carbon dioxide by contact with water – with the help of the carbonate salts of the tablets. To adequately inform patients about the possible erosive potential of effervescent tablets, this study was underta...

Quality Control and Standardization of Rabeprazole Tablets

Rabeprazole sodium is a new stable pharmaceutical composition developed by us in tablet form, consisting of rabeprazole sodium as active ingredient, excipients, a separating layer and enteric coating. The manufacturing method involves pressing with preliminary wet granulation. In this work, a method was developed for the quantitative determination of rabeprazole sodium in tablets with simultane...

Instability of Sodium Monofluorophosphate in Effervescent Tablets

Sodium monofluorophosphate (MFP, CAS 10163-15-2), widely used as an anti-caries agent and in the prevention or treatment of osteoporosis, is sensitive to moisture and acid. This research presents results of a study of the stability of MFP in tablets from four different pharmaceutical laboratories. With an initial water content of 2.9 to 4.0%, the pH of water solutions of three brands of non-eff...

In-vitro evaluation of erosive potential of vitamin/mineral effervescent tablets commercially available in Switzerland

Formulation, characterization and physicochemical evaluation of ranitidine effervescent tablets.

PURPOSE The aim of this study was to design, formulate and physicochemically evaluate effervescent ranitidine hydrochloride (HCl) tablets since they are easily administered while the elderly and children sometimes have difficulties in swallowing oral dosage forms. METHODS Effervescent ranitidine HCl tablets were prepared in a dosage of 300 mg by fusion and direct compression methods. The powd...